Levofloxacin-Resistant Pneumococcus

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منابع مشابه

Penicillin resistant pneumococcus.

Resistance to other antimicrobial agents and chloramphenicol has also been reported. 4,5 Multiple resistant strains have been responsible for infection with a high mortality rate. 5 To our knowledge, isolation of penicillin resistant pneumococci has not been documented in this region. We report the isolation of a penicillin resistant strain from the throat of an eleven-month old baby boy and th...

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Levofloxacin-Resistant Haemophilus influenzae, Taiwan, 2004–2010

Levofloxacin resistance in Haemophilus influenzae has increased significantly in Taiwan, from 2.0% in 2004 to 24.3% in 2010 (p<0.001). Clinical and molecular investigations of 182 levofloxacin-resistant isolates revealed that the increase was mainly the result of the spread of several clones in the elderly population in different regions.

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Penicillin-resistant pneumococcus and risk of treatment failure in pneumonia.

OBJECTIVE To determine whether the presence of in vitro penicillin-resistant Streptococcus pneumoniae increases the risk of clinical failure in children hospitalised with severe pneumonia and treated with penicillin/ampicillin. DESIGN Multicentre, prospective, observational study. SETTING 12 tertiary-care centres in three countries in Latin America. PATIENTS 240 children aged 3-59 months,...

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Fluoroquinolone-resistant Streptococcus pneumoniae associated with levofloxacin therapy.

Fluoroquinolone-resistant cultures of Streptococcus pneumoniae were isolated from 2 patients who were treated for pneumonia with levofloxacin. Nucleotide sequence analysis of bacterial DNA showed that the isolates contained mutations in both parC (DNA topoisomerase IV) and gyrA (DNA gyrase), which were shown previously to confer fluoroquinolone resistance. With the resistant isolates, the MICs ...

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Levofloxacin: serum bactericidal activity against methicillin-resistant Staphylococcus aureus isolates.

The aim of this study was to assess the serum bactericidal activity (SBA) of levofloxacin compared with that of ofloxacin against methicillin-resistant Staphylococcus aureus (MRSA) isolates. Serum from 10 healthy volunteers (seven females, three males) was collected after a single oral dose of either levofloxacin (500 mg) or ofloxacin (400 mg). Subjects were allocated randomly to treatment afte...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2000

ISSN: 1058-4838,1537-6591

DOI: 10.1086/313958